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Title: Non-Invasive Method Of Measuring Distributed Impedance Of Neuron Fibers
Author: Boguslaw Kuszta, Cynthia Husted
Source: 2000 Measurement Science Conference
Year Published: 2000
Abstract: A method is proposed for non-invasively determining the impedance along a branch of a neuron tree using voltage sensitive dyes and fiber tree morphology obtained from computerized image analysis. Using the concept of Tellegen adjoint networks in combination with voltage changed allows effective impedance computation of selected fibers. The primary function of nerves is to process electrical (electrochemical?) signals. The velocity of signal propagation and computational capabilities of the nervous system depend on the impedances of the all branches of a dendritic tree. Despite the apparent triviality of computing the impedance as a ratio of the voltage drop along the fiber to the current in the fiber, real measurements are difficult and yield conflicting results. The main reasons for difficulties are the complex morphologies of dendritic trees and a lack of truly non-invasive methods of current injection and voltage measurements.

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